View abstract. Phytother Res. Licorice is an herb that grows in parts of Europe and Asia. 1987;(10):46-48. Taking peony root along with phenytoin might decrease the effects of phenytoin and increase the risk of seizures. We could use compounds in these foods to . N Engl J Med 1991;325:1223-7. View abstract. View abstract. [Paeonia Lactiflora injection in treating chronic cor pulmonale with pulmonary hypertension]. Am J Med Sci 2003;325:153-6. This is a partial list of herbs and herbal treatments with known or suspected adverse effects, either alone or in interaction with other herbs or drugs.Non-inclusion of an herb in this list does not imply that it is free of adverse effects. A randomized, crossover comparison of herbal medicine and bromocriptine against risperidone-induced hyperprolactinemia in patients with schizophrenia. Peony root might decrease the amount of phenytoin in the body. View abstract. J Biol Response Mod 1985;4:551-84. Effect of glycyrrhizin on the activity of CYP3A enzyme in humans. Isr J Dent Sci 1989;2(3):153-157. Radix Paeoniae Alba increases serum estrogen level and up-regulates estrogen receptor expression in uterus and vagina of immature/ovariectomized mice. (Glycyrrhiza glabra), it performs better, especially for relaxing muscles, reducing painful menstruation, as well as lowering serum and free testosterone levels in women with PCOS. Ann Pharmacother 2003;37(6):836-838. Exp Ther Med 2016;11(3):1135-41. Sakamoto S, Kudo H, Suzuki S, et al. The combination of Licorice and Peony has been used in TCM for centuries and now used extensively in western herbal medicine for ovarian cysts and PCOS. Bian, X., Xu, Y., Zhu, L., Gao, P., Liu, X., Liu, S., Qian, M., Gai, M., Yang, J., and Wu, Y. View abstract. Paeonia lactiflora : Peony is another popular anti-androgenic herb. Xu, L., Jiang, J., and Du, F. Z. View abstract. OTHER NAME(S): Bai Shao, Chi Shao, Chinese Peony, Common Peony, C. Peony (Paeonia lactiflora) is an herb. Licorice root contains glycyrrhizin, which can cause side effects when eaten in large amounts. Additional reporting by Meghan De Maria. J Neuroophthalmol. Ai, M., Yamaguchi, T., Odaka, T., Mitsuhashi, K., Shishido, T., Yan, J., Seza, A., and Saisho, H. Objective assessment of the antispasmodic effect of shakuyaku-kanzo-to (TJ-68), a Chinese herbal medicine, on the colonic wall by direct spraying during colonoscopy. View abstract. Cooper, H., Bhattacharya, B., Verma, V., McCulloch, A. J., Smellie, W. S., and Heald, A. H. Liquorice and soy sauce, a life-saving concoction in a patient with Addison's disease. View abstract. View abstract. Other conditions. Hussain RM. 17. Taking peony along with estrogen might increase the effects and side effects from estrogen. Nephol Dial Transplant 1999;14:218-20. Heidemann HT, Kreuzfelder E. Hypokalemic rhabdomyolysis with myoglobinuria due to licorice ingestion and diuretic treatment. J Altern Complement Med. 2013 Nov;18(6):593-6. Clin Rheumatol. WebMD does not provide medical advice, diagnosis or treatment. It contains kojic acid, witch hazel, and licorice extracts that reduce melanin production and exfoliate . View abstract. View abstract. View abstract. Read about Peony uses, side effects, health benefits, interactions, dose, warnings, and precautions. Antiviral Res 1987;7(3):127-137. Shintani, S., Murase, H., Tsukagoshi, H., and Shiigai, T. Glycyrrhizin (licorice)-induced hypokalemic myopathy. Side effects, toxicity, and interactions. Comparative study of bioactive constituents in crude and processed Glycyrrhizae radix and their respective metabolic profiles in gastrointestinal tract in vitro by HPLC-DAD and HPLC-ESI/MS analyses. Man SC, Li XB, Wang HH, et al. Int Immunopharmacol. Clin Ter 1990;132(1):55-58. [Clinical study on effect of recombinant roasted licorice decoction combined with low-dose glucocorticoids in treating idiopathic thrombocytopenic purpura]. Taking too much licorice can cause high blood pressure. Effect of glycyrrhizin on viral replication and quasispecies in patients with type C chronic hepatitis. 2017 Sep;31(9):1330-1340. Chen, W. G. and Ba, Z. M. Prof. ZHANG Yi's experience in treating severe arrhythmia. As I've all but cut out alcohol, I've tended to drink this tea before going to bed and sometimes during the day. View abstract. Low doses of liquorice can induce hypertension encephalopathy. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Phytother Res. Review of over-the-counter treatments for aphthous ulceration and results from use of a dissolving oral patch containing glycyrrhiza complex herbal extract. The chemicals in licorice are thought to . Lee, S. J., Lee, H. M., Ji, S. T., Lee, S. R., Mar, W., and Gho, Y. S. 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose blocks endothelial cell growth and tube formation through inhibition of VEGF binding to VEGF receptor. View abstract. Licorice root and white peony for PCOS. Yamada, K., Kanba, S., Yagi, G., and Asai, M. Effectiveness of herbal medicine (shakuyaku-kanzo-to) for neuroleptic-induced hyperprolactinemia. Chewing tobacco flavored with Licorice may cause serious side effects such as high blood pressure. View abstract. J Pharm Pharmacol 2003;55:1275-82. Licorice reduces body fat mass in obese men and women. Lancet 2000;355(9198):134-138. It may disrupt the production of sex hormones ( 9 ). Hataya Y, Oba A, Yamashita T, Komatsu Y. Hyponatremia in an elderly patient due to isolated hypoaldosteronism occurring after licorice withdrawal. Armanini D, De Palo CB, Mattarello MJ, et al. Heavy consumption of licorice during pregnancy has been associated with premature birth and health problems in the child. 2013 Sep;117(3):614-21. Oh, G. S., Pae, H. O., Choi, B. M., Jeong, S., Oh, H., Oh, C. S., Rho, Y. D., Kim, D. H., Shin, M. K., and Chung, H. T. Inhibitory effects of the root cortex of Paeonia suffruticosa on interleukin-8 and macrophage chemoattractant protein-1 secretions in U937 cells. Antiviral Res 1987;7(2):99-107. Effect of orally administered shao-yao-gan-cao-tang (Shakuyaku-kanzo-to) on muscle cramps in maintenance hemodialysis patients: a preliminary study. Exp Med Surg 1969;27:411-20. Jia, Y. Hyodo T, Taira T, Kumakura M, et al. 2009;14(1):64-65. Double-blind, placebo-controlled, randomized, pilot clinical trial of ImmunoGuard--a standardized fixed combination of Andrographis paniculata Nees, with Eleutherococcus senticosus Maxim, Schizandra chinensis Bail. Am J Chin Med 2003;31:445-53. . 2020;2020:3727682. Maeda T, Shinozuka K, Baba K, et al. View abstract. 1. Arentz S, Smith CA, Abbott J, Fahey P, Cheema BS, Bensoussan A. Oh, G. S., Pae, H. O., Choi, B. M., Lee, H. S., Kim, I. K., Yun, Y. G., Kim, J. D., and Chung, H. T. Penta-O-galloyl-beta-D-glucose inhibits phorbol myristate acetate-induced interleukin-8 [correction of intereukin-8] gene expression in human monocytic U937 cells through its inactivation of nuclear factor-kappaB. J Tradit.Chin Med 2010;30(1):47-50. Prevention of maternal-fetal blood group incompatibility with traditional Chinese herbal medicine. But I didn't take it long enough to see any change. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11. View abstract. Takahara T, Watanabe A, Shiraki K. Effects of glycyrrhizin on hepatitis B surface antigen: a biochemical and morphological study. Pseudohyperaldosteronism, liquorice, and hypertension. Hasegawa, J., Suyama, Y., Kinugawa, T., Morisawa, T., and Kishimoto, Y. Echocardiographic findings of the heart resembling dilated cardiomyopathy during hypokalemic myopathy due to licorice-induced pseudoaldosteronism. Brasseur, A. and Ducobu, J. Chin J Integr Med 2022. View abstract. Practitioners still sometimes suggest whole licorice for cough . Taking licorice and loop diuretics together might make potassium levels drop too low. View abstract. Nephron 2002;90:240. Some of these health benefits have also . View abstract. A. and Myers, S. P. Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study. Some medications are moved in and out of cells by pumps. Armanini, D., Mattarello, M. J., Fiore, C., Bonanni, G., Scaroni, C., Sartorato, P., and Palermo, M. Licorice reduces serum testosterone in healthy women. View abstract. Nasal irrigation with Glycyrrhiza glabra extract for treatment of allergic rhinitis - A study of in vitro, in vivo and clinical trial. Side effects of peony tea! Early evidence suggests that taking 45 grams of a specific product containing peony and licorice (Peony-Glycyrrhiza Decoction, PGD) daily for 4 weeks reduces levels of a hormone called prolactin in women with high levels of prolactin, without affecting other hormone levels or mental symptoms. Wang H, Dong L, Qu F, et al. Some research studies have found Angelica Sinensis to be beneficial for its effects on some symptoms of menopause. Epilepsy Res 2021;176:106735. Med Princ Pract 2010;19(6):485-489. N Engl J Med. View abstract. All rights reserved. WebMD does not provide medical advice, diagnosis or treatment. View abstract. Liang, R. N., Liu, J., and Lu, J. Mamgain RK, Gupta M, Mamgain P, et al. All rights reserved. The Potential Benefits and Side Effects of the White Peony Root. View abstract. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. View abstract. Qi XG. 2020;383(13):1263-1275. J Clin Psychopharmacol 1997;17(3):234-235. View abstract. Elinav E, Chajek-Shaul T. Licorice consumption causing severe hypokalemic paralysis. Eur J Clin Pharmacol 2010;66(8):805-810. J Contemp Dent Pract 2010;11(1):E088-E094. Aldosterone is a hormone that causes your body to retain salt (sodium) and lose potassium. Korri, H., Awada, A., Baajour, W., Beaini, M., and Nasreddine, W. [Rapidly progressing quadriparesis secondary to licorice (souss) intoxication]. Life Sci 9-27-2002;71(19):2267-2277. (Tokyo) 2008;54(3):244-249. Licorice or Mulethi, also known as "Sweetwood", is an effective and potent medicinal herb. View abstract. Steroids 2004;69(11-12):763-766. Lancet 1990;335(8697):1060-3. Lozenge-induced hypermineralcorticoid state--a unique case of licorice lozenges resulting in hypertension and hypokalemia. Lapi F, Gallo E, Bernasconi S, et al. View abstract. Mechanisms involved in the therapeutic effects of Paeonia lactiflora Pallas in rheumatoid arthritis. MacKenzie, M. A., Hoefnagels, W. H., Jansen, R. W., Benraad, T. J., and Kloppenborg, P. W. The influence of glycyrrhetinic acid on plasma cortisol and cortisone in healthy young volunteers. 2017;109:182-190. Kinoshita, H., Okabayashi, M., Kaneko, M., Yasuda, M., Abe, K., Machida, A., Ohkubo, T., Kamata, T., and Yakushiji, F. Shakuyaku-kanzo-to induces pseudoaldosteronism characterized by hypokalemia, rhabdomyolysis, metabolic alkalosis with respiratory compensation, and increased urinary cortisol levels. Dong quai grows at high altitudes in the cold, damp, mountains of China, Korea, and Japan. View abstract. For people who already have high blood pressure or heart or kidney disease, as little as 5 g/day can cause these side effects. Because of its beneficial effects, the licorice root has been dubbed the "Medicinal plant of 2012." Now scientists have discovered that licorice root from the papilionaceae or leguminous family . View abstract. J Altern Complement Med 2000;6:557-9. A. Cisplatin is used to treat cancer. It's thought liquorice's side-effects are caused by the glycyrrhizic acid, but it is possible to buy deglycyrrhizinated liquorice (DGL), which may help prevent these issues. van Beers, E. J., Stam, J., and van den Bergh, W. M. Licorice consumption as a cause of posterior reversible encephalopathy syndrome: a case report. View abstract. Middle East J Anaesthesiol. Licorice extract inhibits the production of tyrosinase, in turn inhibiting the production of dark spots. 17. J Clin Psychopharmacol 2016;36(6):572-9. $9.44 $ 9. Iran J Pharm Res 2012;11(2):541-8. View abstract. Efficacy and tolerability of hydroalcoholic extract of Paeonia officinalis in children with intractable epilepsy: An open-label pilot study. White peony root is very much essential and used in Chinese medicine because of its medicinal properties. Pharmazie 2010;65(8):624-8. Feng ZT, Xu J, He GC, Cai SJ, Li J, Mei ZG. Okubo T, Nagai F, Seto T, et al. View abstract. Alt Med Rev 2001;6:495-9. Arase, Y., Ikeda, K., Murashima, N., Chayama, K., Tsubota, A., Koida, I., Suzuki, Y., Saitoh, S., Kobayashi, M., and Kumada, H. The long term efficacy of glycyrrhizin in chronic hepatitis C patients. Cancer Lett. There is only one reminder that peony tea contains caffeine. 2020;16(3):458-462. Clinical reduction of S. mutans in pre-school children using a novel liquorice root extract lollipop: a pilot study. I. Elucidation of five new flavonoid constituents from the roots of Glycyrrhiza glabra L. collected in Xinjiang. View abstract. Licorice is Sita (cold) in nature, Guru (heavy) to digest, and Madhura (sweet) in . View abstract. Kroes, B. H., Beukelman, C. J., van den Berg, A. J., Wolbink, G. J., van Dijk, H., and Labadie, R. P. Inhibition of human complement by beta-glycyrrhetinic acid. American Herbal Products Association's Botanical Safety Handbook, Second Edition. Hyodo T, Taira T, Kumakura M, et al. Licorice root and white poney is a common herbal formula for PCOS originating in traditional Chinese medicine. Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents. Costa, A., Moises, T. A., Cordero, T., Alves, C. R., and Marmirori, J. A Rutgers expert discusses how eating black licorice can affect your health. G Ital Dermatol Venereol 2010;145(6):789-792. View abstract. Peony and Licorice is a safe and gentle yet powerful formula that is famous for its ability to build blood and balance menstrual cycles. View abstract. 4-14-2001;145(15):744-747. Therapeutic Research Faculty 2020. Sontia B, Mooney J, Gaudet L, Touyz RM. An Bras Dermatol 2010;85(5):613-620. J Agric Food Chem 6-13-2007;55(12):4691-4697. 1999;15:499-523. View abstract. World J Gastroenterol 2005;11:2124-9. . Estrogenic and antiproliferative properties of glabridin from licorice in human breast cancer cells. Oh, G. S., Pae, H. O., Oh, H., Hong, S. G., Kim, I. K., Chai, K. Y., Yun, Y. G., Kwon, T. O., and Chung, H. T. In vitro anti-proliferative effect of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose on human hepatocellular carcinoma cell line, SK-HEP-1 cells. Fiore, C., Eisenhut, M., Krausse, R., Ragazzi, E., Pellati, D., Armanini, D., and Bielenberg, J. Antiviral effects of Glycyrrhiza species. N Engl J Med 1999;341:1158. J Telemed Telecare. Hypertension and the cortisol-cortisone shuttle. Peony might slow blood clotting. View abstract. Ruetzler K, Fleck M, Nabecker S, Pinter K, Landskron G, Lassnigg A, You J, Sessler DI. J Nutr 2001;131:1471-8. View abstract. View abstract. View abstract. Exp.Mol.Med 12-31-2003;35(6):467-474. Neth J Med 2005;63:146-8. Nishioka, K. and Seguchi, T. Contact allergy due to oil-soluble licorice extracts in cosmetic products. Licorice might decrease how well cisplatin works. Liapina LA, Ammosova IaM, Novikov VS, et al. 6. A controlled trial of traditional Chinese herbal medicine in Chinese patients with recalcitrant atopic dermatitis. The author has an hindex of 4, co-authored 18 publication(s) receiving 46 citation(s). 1991;78(1-2):1-6. Contact Dermatitis 1989; 20:152-3.. View abstract. Drug Metab Dispos 2002;30:709-15.. View abstract. View abstract. View abstract. The 1:1 of peony and licorice group can significantly reduced the ureteral smooth muscle tension and Christina Loosestrife herb can increase the u reteral tension, but the amount is too large, the mechanism may be related with the diuretic row stone. Yasue H, Itoh T, Mizuno Y, Harada E. Severe hypokalemia, rhabdomyolysis, muscle paralysis, and respiratory impairment in a hypertensive patient taking herbal medicines containing licorice. Select a condition to view a list of vitamins. Phytother Res 2009;23(2):246-250. Panduranga P, Al-Rawahi N. Licorice-induced severe hypokalemia with recurrent torsade de pointes. View abstract. Effects of cerebral ischemia-reperfusion on pharmacokinetic fate of paeoniflorin after intravenous administration of Paeoniae Radix extract in rats. Cassano, N., Mantegazza, R., Battaglini, S., Apruzzi, D., Loconsole, F., and Vena, G. A. Hukkanen J, Ukkola O, Savolainen MJ. and Glycyrrhiza glabra L. extracts in patients with Familial Mediterranean Fever. Zhu Q, Qi X, Wu Y, Wang K. Clinical study of total glucosides of paeony for the treatment of diabetic kidney disease in patients with diabetes mellitus. Melzer J, Rosch W, Reichling J, et al. Z Kardiol 1991;80(6):389-391. Phytotherapy Research 1997;11:207-210. van Gelderen, C. E., Bijlsma, J. Endocrinol Jpn 1990;37:331-41. View abstract. Treatment of duodenal ulcer with glycyrrhizinic-acid-reduced liquorice. Wang H, Wei W, Wang NP, et al. Paeonia lactiflora (Chinese peony) and Paeonia brownii (California peony) relax smooth muscle tissue with a particular affinity for the female reproductive tract. This might decrease the effects of midazolam. View abstract. View abstract. 1994;14:207-9, 195. . Chien, C. F., Wu, Y. T., and Tsai, T. H. Biological analysis of herbal medicines used for the treatment of liver diseases. Isaia, G. C., Pellissetto, C., Ravazzoli, M., and Tamone, C. Acute adrenal crisis and hypercalcemia in a patient assuming high liquorice doses. The licorice root derived isoflavan glabridin inhibits the activities of human cytochrome P450S 3A4, 2B6, and 2C9. View abstract. Werner, S., Brismar, K., and Olsson, S. Hyperprolactinaemia and liquorice. This could change the effects and side effects of these medications.
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